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December 19, 2025

Ulcerative Colitis

 


The diagnosis of UC is best made with endoscopy and mucosal biopsy for

 histopathology. Laboratory studies are helpful to exclude other diagnoses and assess

 the patient's nutritional status, but serologic markers can assist in the diagnosis of

 inflammatory bowel disease. Radiographic imaging has an important role in the

 workup of patients with suspected inflammatory bowel disease and in the

 differentiation of UC from Crohn disease by demonstrating fistulae or the presence of

 small bowel disease seen only in Crohn disease.

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